Er kroppen rar?

CD2 expression and the PML-RAR gene.

On weakly eR-open functions

The main goal of this paper is to introduce and study a new class of function via the notions of $e$-$theta$-open sets and $e$-$theta$-closure operator which are defined by Özkoç and Aslım [10] called weakly $eR$-open functions and $e$-$theta$-open functions. Moreover, we investigate not only some of their basic properties but also their relationships with other types of already existing topolo...

The Retinoic Acid Receptor (RAR ) Chimeric Proteins PML-, PLZF-, NPM-, and NuMA-RAR Have Distinct Intracellular Localization Patterns

Retinoic acid receptor (RAR ) gene rearrangement by reciprocal chromosome translocation is the molecular signature of acute promyelocytic leukemia (APL). Disruption of RAR function appears to be the likely cause of aberrant myelopoiesis observed in APL, because PML-RAR expression has been shown to deregulate the transcription of genes that control myelopoiesis. To target RAR chimeric proteins, ...

P42: Luteolin Counteracts ER Stress in PC12 Cells through Moderating ER Chaperones and Heat Shock Proteins

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Opposing effects of PML and PML/RAR on STAT3 activity

Promyelocytic leukemia protein PML acts as a tumor suppressor, whereas its chimeric mutant promyelocytic leukemia/ retinoic acid receptor (PML/RAR ) causes acute promyelocytic leukemia (APL). Because PML has been shown to form transcription-regulatory complexes with various molecules, we speculated that PML and/or PML/RAR might affect signal transducer and activator of transcription 3 (STAT3) a...